exasperation
Ex*as`per*a"tion, n. Etym: [L. exasperatio: cf. F. exaspération.] 1. The act of exasperating or the state of being exasperated; irritation; keen or bitter anger. Extorted from him by the exasperation of his spirits. South. 2. Increase of violence or malignity; aggravation; exacerbation. "Exasperation of the fits." Sir H. Wotton.